Cholinesterase
Inhibitors
The acute dosage of a cholinesterase inhibitor of
10-7M inhibits acetyl cholinesterase and kills the insect by shutting
off its
nerves. At the smaller dosage of 10-9M these same molecules will
inhibit juvenile hormone carboxyesterase. The juvenile hormone
regulates the gonotrophic cycle and egg development, not just in
mosquitoes. In Tetranichid mites it will increase the egg
production to have sub-acute exposures to that chemical. In
mosquitoes it will make them bite more frequently. In such a
situation the incidence of mosquito bites and disease transmission
could go up and not down.