Cholinesterase Inhibitors

    The acute dosage of a cholinesterase inhibitor of 10-7M inhibits acetyl cholinesterase and kills the insect by shutting off its nerves. At the smaller dosage of 10-9M these same molecules will inhibit juvenile hormone carboxyesterase.  The juvenile hormone regulates the gonotrophic cycle and egg development, not just in mosquitoes.  In Tetranichid mites it will increase the egg production to have sub-acute exposures to that chemical.  In mosquitoes it will make them bite more frequently.  In such a situation the incidence of mosquito bites and disease transmission could go up and not down.